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Journal of Neurosonology 2017;9(1):1-6.
Published online November 30, 2017.
Standardized Transcranial Doppler Protocol for Clinical Study
Kwanghyun Kim, MD1, Hye Rin Yoon, MD1, Sang Won Han, MD1, Sook Young Roh, MD, PhD2
1Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
2Department of Neurology, Bundang Jesaeng General Hospital, Seongnam, Korea
임상 연구를 위한 경두개 도플러 초음파 검사 표준화
김광현1, 윤혜린1, 한상원1, 노숙영2
1인제대학교 의과대학 상계백병원 신경과
2분당제생병원 신경과
Correspondence:  Sook Young Roh, MD, PhD, Tel: +82-31-779-0216, Fax: +82-31-779-0897, 
Email: syrohnu@dmc.or.kr
Received: 10 May 2017   • Accepted: 9 June 2017
Abstract
Transcranial Doppler (TCD) is a physiological ultrasound test with established safety and efficacy. In recent years, TCD has become a general practice in the diagnostic and monitoring study of cerebral hemodynamics. The noninvasiveness, convenience, and repeatability of TCD examination could promote its clinical and research applications will continue to increase in many brain diseases. It is also the most convenient way to monitor vascular changes in response to therapeutic interventions. However, it is highly operator dependent with the handheld technique requiring detailed three-dimensional knowledge of cerebrovascular anatomy and experience for accurate interpretation. Therefore, a standardized protocol, based on accepted TCD practice, is essential for the clinical study using TCD. Standardized scanning protocol with transducer positioning and orientation, depth selection and vessel identification will support TCD research applications. This article aims to provide an overview of a few clinical TCD studies and introduce standardized TCD protocols. A brief outline is provided of its role and limitations in its diverse applications.
Key Words: Doppler Transcranial Sonography; Stroke, Practical Clinical Trials


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