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Journal of Neurosonology 2017;9(1):12-17.
Published online November 30, 2017.
Relationship between 10-year Cardiovascular Risk and Carotid Intima-media Thickness in Medical Check-up Participants
Kwanghyun Kim, MD1, Hye Rin Yoon, MD1, Hye-Weon Kim, MD1, Hyo Suk Nam, MD, PhD2, Sang Won Han, MD1, Jeong Yeon Kim, MD, PhD1, Jae Hyun Park, MD, PhD1, Hyun-jeung Yu, MD, PhD3
1Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
3Department of Neurology, Bundang Jesaeng General Hospital, Seongnam, Korea
건강검진 참여자에서 관찰한 심혈관 질환 발생위험도와 경동맥 내중막 두께와의 관계
김광현1, 윤혜린1, 김혜원1, 남효석2, 한상원1, 김정연1, 박재현1, 유현정3
1인제대학교 의과대학 상계백병원 신경과
2연세대학교 의과대학 신경과학교실
3분당제생병원 신경과
Correspondence:  Hyun-jeung Yu, MD, PhD, Tel: +82-31-779-0216, Fax: +82-31-779-0897, 
Email: yhj314@dmc.or.kr
Received: 6 September 2017   • Accepted: 30 November 2017
Abstract
Background
To assess the relationship between 10-year cardiovascular risk and carotid intima-media thickness (IMT) in medical check-up participants.
Methods
The participants who underwent a medical check-up were enrolled into this study. Adults aged 50 to 69 years were eligible if they did not have a history of atherosclerotic cardiovascular disease (ASCVD) or stroke. The 10-year CVD risk was calculated using the ASCVD risk estimator (http://tools.acc.org/ASCVD-Risk-Estimator). For the study, the maximum IMT of both carotid arteries were measured and the mean value of them was used for analysis.
Results
A total of 265 participants were enrolled in this study. The mean age was 58 years, and 28% of the participants were women. The mean IMT was significantly correlated with the 10-year CVD risk in all participants (r=0.180, p=0.003). Among men, the mean IMT was 0.81±0.13 mm and 64 (33.5%) participants had ≥10% 10-year CVD risk. There was significant difference in the mean IMT between ≥10% 10-year CVD risk group and <10% 10-year CVD risk group (p=0.025). With women, the mean IMT was 0.78±0.10 mm and 6 (8.1%) participants had ≥10% 10-year CVD risk. No significant difference was observed in the mean IMT between the groups (p=0.291).

Conclusion
s

Whilst routine sonographic screening for carotid artery stenosis has little supporting evidence, our study suggested that there may be an opportunity for decreasing the rate of CVD and stroke through the tailored sonographic examination in high risk subjects.
Key Words: Cardiovascular disease, Carotid intima-media thickness, Primary prevention, Doppler ultrasonography
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